The FDA has invalidated food facility registrations that failed to renew during the 2016 biennial period.  In addition, food facility registrations were invalided for failure of confirmation by a US Agent and/or foreign manufacturer as required under the FDA Food Safety Modernization Act (FSMA).  U.S. Customs message on this matter: https://apps.cbp.gov/csms/viewmssg.asp?Recid=22483&page=&srch_argv=fda&srchtype=&btype=&sortby=&sby=